Archive for the 'Novel Treatments & Drugs' Category

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Immunotherapy – What Side Effects Can You Expect?

As the success of immunotherapy treatments in improving survival and symptom management for cancer patients have started to become known, those suffering from cancer such as mesothelioma and lung cancer may now be given options in terms of the best course of treatment. Immunotherapy works with the body’s own natural defense system by strengthening and

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ONCOS-102 Update: Mesothelioma Patients Responded after Phase II Clinical Trial

Advancement in mesothelioma treatments over the past decade has been relativity stagnant, according to Targovax  – a Norwegian immune-cology company dedicated to the study and research of immunotherapy treatments. However, those suffering from mesothelioma have hope, as continuing phases of clinical trials are showing positive results; the latest being ONCOS-12, an immunotherapy treatment that showed

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Aerosol Chemotherapy – Targeting Peritoneal Mesothelioma Through Pressurized Medicine

Peritoneal mesothelioma is an incredibly rare form of cancer that affects the peritoneum, or abdominal lining. It is not entirely understood how exposure to asbestos causes this type of cancer, but scientists and researchers theorize that ingested asbestos fibers work themselves into the peritoneal cavity, or if inhaled, are transported through the lymph node system.

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New Surgical Technique Could Be Ideal for Patients with Advanced Pleural Mesothelioma

Pleural mesothelioma is a rare and aggressive cancer that has been notoriously difficult to treat. Caused by asbestos exposure, the latency period between the time of initial exposure and disease spans decades and generally by the time the cancer is detected, it is highly advanced. Surgical treatments for those with pleural mesothelioma are generally more

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Immunotherapy May Help Extend the Lives of Lung Cancer and Mesothelioma Patients

Immunotherapy is revolutionizing the health care industry by adding extra years of life to people with lung cancer. A few years ago it was rare for patients with an advanced stage of this disease to live past two years but today it has become more common to do so. Immunotherapy treatment works by boosting immune

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Immunotherapy Treatment Durvalumab Enters Phase II Clinical Trial

While there is no cure for mesothelioma, those who are able to withstand surgery in general may have a better chance of survival, as the cancer is being physically removed. However, mesothelioma is a difficult cancer and often surgery is not an option, and the cancer is unresectable. The success of immunotherapy treatments for cancer

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Biomarker CD47 as a Successful Diagnostic and Treatment Tool

Survival rates for diffuse mesothelioma are notoriously low with the median survival ranging between 12 to 22 months.  A contributing factor to treatment being ineffective is that the disease if often in the advanced stages by the time it is noticed and diagnosed. Early detection may be a key factor in fighting this illness effectively,

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Clinical Trial Investigates Multimodality Treatment for Pleural and Peritoneal Mesothelioma

Researchers at the Memorial Sloan Kettering Cancer Center are collaborating with Pfizer to study the effects of immunotherapy treatment Avelumab when combined with stereotactic body radiation therapy, or SBRT, for those suffering from mesothelioma. SBRT treatments use a device called a linear accelerator that delivers precise and intense doses of radiation to target cancer cells

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Effective Chemotherapy May Rest Upon Reducing Overactive Enzyme

Chemotherapy for mesothelioma patients has been notoriously difficult and the cancer continues to be overwhelmingly unresponsive to such treatment in many cases. However, researchers and scientists have been continually investigating new techniques that involve adjusting how chemotherapy reacts on a cellular level. A study published in the Frontiers in Pharmacology examines a specific enzyme that

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Gene Therapy and DNA Sequencing for Malignant Mesothelioma

Genes are the basic unit of DNA that creates unique proteins used for specific cellular function. The expression of that gene creates an effect and if a gene cannot make a specific protein, this can lead some health risks or problems. A multifactorial disorder, like cancer, heart disease, and diabetes, are the result of multiple

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ONCOS-102 Passes Safety Evaluation in Phase I Clinical Trials, Phase II Clinical Trial Recommended

A new immunotherapy developed by Targovax has recently passed Phase I clinical trials and is set to begin Phase II evaluation of this new treatment that may help those suffering from mesothelioma. ONCOS-102 was used in separate Phase I clinical trials; one in combination with chemotherapy, and one with immunotherapy. Cisplatin and pemetrexed are two

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Legitimate Data and Research is Required for Treatment Approval

For cancer patients who have little success with traditional chemotherapy and radiation treatments, immunotherapy treatments are becoming known alternatives – working with the body’s own immune system to become stronger and better able to fight cancer cells and other infections. A mesothelioma diagnosis is often grim, with survival rates at approximately one year at diagnosis.

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Autophagy Inhibitors Potentially Make Chemotherapy More Effective in Mesothelioma Patients

Autophagy is a natural and regulated self-degradative process in cells that plays a critical role in balancing sources of energy and removing aggravated proteins, damaged organelles, and pathogens. During autophagy, cells break down and recycle their different parts in order to make new cells. In mesothelioma, autophagy is necessary for mesothelial cell growth. A recent

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Bevacizumab – A Positive Treatment with Serious Side Effects

Bevacizumab (Avastin) is commonly viewed as chemotherapy treatment because when administered intravenously, it is particularly effective in controlling such illnesses such as lung cancer and colon cancer. However, it is a bit different than traditional chemotherapy treatments, which directly attack cancer cells. Bevacizumab fights cancer cells by cutting off oxygen and other nutrients the cells

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The Effectiveness of Cisplatin and Pemetrexed in Pericardial Mesothelioma

Out of all the types of mesothelioma, pericardial mesothelioma is one of the rarest forms, accounting for only 0.002% of all known diagnosed mesothelioma cases. Mesothelioma is caused by asbestos exposure, and despite this knowledge and years of research, scientists and researchers still do not have a clear answer as to how the asbestos fibers

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Last update: March 06, 2014. 08:41:31 pm.