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Trimodality Therapy Increases Survival; Immunotherapy Treatment Approved by FDA

Since mesothelioma is often difficult to treat, scientists and researchers look to combination treatments and therapies to improve chances of patients’ survival. There is no “one” treatment that is used across the board in treating mesothelioma, because patients react differently, whether it is to chemotherapy, radiation therapy, immunotherapy, or surgery.  A research team from MD

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Mesothelioma Treatments Used Alongside Surgery – A Clinical Trial

Rare and aggressive in nature, mesothelioma is often a fatal cancer mainly due to its lack of response to most treatments. Surgical options have a higher chance of success for those in the early stages of the disease, but since there is a long latency period between asbestos exposure and symptoms of mesothelioma, often times

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Asbestos Fibers Just As Deadly Regardless of Size

Recognized as one of the six types of asbestos, tremolite is considered to be one of the more deadly forms of asbestos due to its long, sharp, needle-like fibers that are easily inhaled and embedded in the soft tissue of the lungs and surrounding organs. Tremolite is generally found in other minerals such as vermiculite,

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Two Potential Mesothelioma Treatments Have No Positive Effect

Tremelimumab Earlier in the spring of 2017, scientists and researchers from the University of Salford in the UK published a special report questioning the effectiveness of the new immunotherapy treatment known as tremelimumab. Trials of the check point inhibitor did not show promising results and there was concern about the drug’s effectiveness, safety, and tolerability.

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Improvements in Radiation Therapies Give More Treatment Options

When it comes to different treatments for mesothelioma patients, there is no shortage of diversity, as options include chemotherapy, radiation, surgery, immune-based therapies, gene-based therapies, and more. Chemotherapy treatments cisplatin and pemetrexed are first line treatments, especially among those who do not quality for surgery. Radiation treatment is available, but is typically the path less

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Multiple Genetic Variants Increase Mesothelioma Risk

The term “high-risk predisposition,” is a well-known term in the cancer world that means a person could have certain genetic factors or other factors that places him or her at a higher risk for certain cancers. For mesothelioma, a high risk factor is the mutated BAP1 gene: a tumor suppressor that is responsible for encoding

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Mesothelioma Patients Receive Zoledronic Acid as Treatment

Known as a bisphosphonate, zoledronic acid is typically used for bone diseases such as osteoporosis, and to treat high calcium levels in the blood that can lead to other health complications.  Nitrogen containing bisphosphonates like zoledronic acid are known to have cancer suppressing qualities, and scientists and researchers were eager to find out if zoledronic

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Time Increases Risk for Mesothelioma, Study Finds

Asbestos-related illnesses such as mesothelioma and asbestosis have been known to develop over a period of decades, affecting people years and years since their last exposure. Many studies over the years have suggested that the length of the amount of time that has passed since initial exposure and subsequent symptoms can increase the risk of

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Giving Cediranib Another Chance

A Phase I study for cediranib, a VEGFR/PDGFR kinase inhibitor, showed promising results in shrinking tumor size and increasing survival rates for those suffering from malignant pleural mesothelioma. This is not the first time cediranib has been studied as a possible treatment for mesothelioma. In 2011/2012 a Phase II trial for cediranib conducted by researchers

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Calretinin More Effective Than Mesothelin in Detecting Mesothelioma Early

Mesothelioma is a rare and aggressive cancer that is difficult to diagnose because symptoms often mimic other diseases such as pulmonary fibrosis or lung cancer. Pathology reports and biopsies help distinguish this cancer from other illnesses, but often patients will have already developed more serious symptoms because the cancer has spread by the time it

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Survival Rates Based Upon Subtypes of Mesothelioma

A recent study published in the British Journal of Cancer compared survival rates of mesothelioma patients that received their diagnosis through either cytological or by histological method for those with the epithelioid, biphasic, or sarcomatoid subtype of mesothelioma. The concern is that those with the biphasic subtype of mesothelioma are under diagnosed when epithelioid mesothelioma

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Phase I Clinical Trial Underway for CAR T-cell Therapy

A Phase I clinical trial for an immunotherapy treatment for malignant pleural mesothelioma and non-small cell lung cancer (NSCLC) is currently underway at the University of Pennsylvania in Philadelphia. Immunotherapy treatments support the body’s immune system response to diseases. It is often looked to as a positive alternative for treating malignancies such as mesothelioma because

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Pembrolizumab Update: Aduro Biotech Collaborates with Merck

A biopharmaceutical company named Aduro Biotech recently announced its collaboration with Merck to further evaluate the findings for the Phase II trial of KEYTRUDA ® (pembrolizumab) and to combine their own immunotherapy treatment, CRS-207. Information regarding KEYRUDA ® treatment began to circulate late last year when data presented at the 17th World Conference on Lung

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Bevacizumab (Avastin): Part of a New Treatment Regimen for Mesothelioma Patients

The results of a 2016 Phase III trial of the monoclonal antibody bevacizumab (Avastin) have established another option for treatment for those suffering from malignant pleural mesothelioma. Angiogenesis, which is the formation of new blood vessels, plays a key role in mesothelioma because it allows the tumors and cancer to spread. However, scientists and researchers

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Surgical Techniques for Mesothelioma

While surgical techniques are not the most common effort when it comes to treating mesothelioma, the pleurectomy/decortication (P/D) is a technique that has been the most successful over the years. A recent study took a look at the different surgical techniques that can be used with P/D and noted the overall effects on the patient.

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Last update: March 06, 2014. 08:41:31 pm.