Archive for the 'Novel Treatments & Drugs' Category

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Giving Cediranib Another Chance

A Phase I study for cediranib, a VEGFR/PDGFR kinase inhibitor, showed promising results in shrinking tumor size and increasing survival rates for those suffering from malignant pleural mesothelioma. This is not the first time cediranib has been studied as a possible treatment for mesothelioma. In 2011/2012 a Phase II trial for cediranib conducted by researchers

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Calretinin More Effective Than Mesothelin in Detecting Mesothelioma Early

Mesothelioma is a rare and aggressive cancer that is difficult to diagnose because symptoms often mimic other diseases such as pulmonary fibrosis or lung cancer. Pathology reports and biopsies help distinguish this cancer from other illnesses, but often patients will have already developed more serious symptoms because the cancer has spread by the time it

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Pembrolizumab Update: Aduro Biotech Collaborates with Merck

A biopharmaceutical company named Aduro Biotech recently announced its collaboration with Merck to further evaluate the findings for the Phase II trial of KEYTRUDA ® (pembrolizumab) and to combine their own immunotherapy treatment, CRS-207. Information regarding KEYRUDA ® treatment began to circulate late last year when data presented at the 17th World Conference on Lung

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Bevacizumab (Avastin): Part of a New Treatment Regimen for Mesothelioma Patients

The results of a 2016 Phase III trial of the monoclonal antibody bevacizumab (Avastin) have established another option for treatment for those suffering from malignant pleural mesothelioma. Angiogenesis, which is the formation of new blood vessels, plays a key role in mesothelioma because it allows the tumors and cancer to spread. However, scientists and researchers

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Success in Lung Cancer Treatment Gives Hope to Mesothelioma Patients

The latest success concerning a treatment for non- small cell lung cancer (NSCLC) has scientists and researchers hopeful that the same treatment can be applied to mesothelioma victims. The Phase III trial for Alecensa (alectinib), while currently not recruiting participants, is on-going and results thus far have shown to be promising for those with NSCLC.

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Nintedanib and Pembrolizumab – Hope for Mesothelioma Patients

The latest findings in cancer treatments for the often fatal mesothelioma have scientists and researchers hopeful that they are one step closer in finding a consistent, effective treatment for the asbestos-caused cancer. The LUME-Meso Phase II trial for patients with malignant pleural mesothelioma focused on the administration of the triple angiokinase inhibitor called Nintedanib. This oral

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Immunotherapy Drug Tremelimumab Not As Effective As Hoped

Mesothelioma’s aggressive nature makes it difficult to treat with common cancer treatments such as chemotherapy and radiation. Scientists and researchers are constantly looking for new ways to treat mesothelioma outside of chemotherapy and radiation, such as gene therapy or immunotherapy. Immunotherapy is a novel approach and sometimes a more viable option for those suffering from

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The Latest Clinical Trial for Nintedanib – Are You a Candidate?

Scientists and researchers are excited over the latest completion of a Phase II clinical trial for those suffering from mesothelioma – an incurable asbestos-caused cancer that has a median survival of only 9 to 12 months.  The LUME-Meso Phase II trial for patients with malignant pleural mesothelioma showed a slight increase in progression-free and overall

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Lack of Treatment Responses for Mesothelioma, Proteins Combat Metastasis

Mesothelioma is an incredibly difficult cancer to treat. Its late stage diagnosis coupled with its aggressive nature leaves victims without very much time to combat this fatal cancer. There are a variety of treatment options available to those suffering from mesothelioma, even though there is no cure. Surgery Radiation Chemotherapy Intraoperative photodynamic therapy Immunotherapy Gene

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Lung-Sparing Surgery Dramatically Improves Prognosis for Mesothelioma Patients

Those suffering from mesothelioma know that the prognosis is grim. The average life expectancy for someone who is recently diagnosed is only eight months. Chemotherapy is the standard treatment for mesothelioma, but in most cases, the cancer is too far advanced for chemotherapy to be effective. Surgery for mesothelioma is possible but results from surgery

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Chemical Components In Peppers and Sea Cucumbers May Combat Mesothelioma

Mesothelioma is difficult to treat for a number of reasons. The long latency period before initial diagnosis means that the cancer is typically in advanced stages by the time it is discovered. A built-up resistance to common cancer treatments also makes it difficult for treatment to have a positive effect on cancer victims. This contributes

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Positive Response for Immunotherapy Treatment KEYTRUDA ®

Scientists and researchers from Merck announced an update on their findings for the Phase 1b KEYNOTE-28 study that involves the investigation of the immunotherapy treatment called KEYTRUDA ® (pembrolizumab). The purpose of this study was to evaluate the safety, tolerability, and the anti-tumor activity of KEYTRUDA ® and focused on patients with small cell lung

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Ptac2S Potentially More Effective Than Cisplatin When Fighting Mesothelioma

Malignant Pleural Mesothelioma (MPM) is a rare, aggressive asbestos –related cancer that has a poor survival rate due to the fact that the cancer is hard to detect early, and once detected, has usually spread and is hard to control. Surgery is typically an effective option for removing cancerous cells, but in some cases, surgery

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Properties in Red Wine Could Help Fight Mesothelioma

Combining different types of treatment when it comes to treating mesothelioma is common because of how aggressive the cancer can be. While some treatments do prove to be effective, the overall prognosis of an individual with this asbestos-related cancer remains dim. A recent study done in Korea carefully evaluated the combination of  cisplatin, a common

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Mesothelioma Awareness Day 2016

September 26, 2016, was Mesothelioma Awareness Day. This day dedicated to raising awareness for mesothelioma, was established in 2004 by the Mesothelioma Applied Research Foundation (MARF). MARF is a nonprofit organization that believes that there is a cure for mesothelioma and through education, fundraising and awareness, a cure can be achieved. Mesothelioma is a deadly

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Last update: March 06, 2014. 08:41:31 pm.